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Carbamoyl phosphate : ウィキペディア英語版 | Carbamoyl phosphate
|Section2= |Section3= }} Carbamoyl phosphate is an anion of biochemical significance. In land-dwelling animals, it is an intermediary metabolite in nitrogen disposal through the urea cycle and the synthesis of pyrimidines. ==Production== It is produced from bicarbonate, ammonia (derived from glutamine), and phosphate (from ATP). The synthesis is catalysed by the enzyme carbamoyl phosphate synthetase, as follows: * HCO3− + ATP → ADP + HO–C(O)–OPO32− (carboxyl phosphate) * HO–C(O)–OPO32− + NH3 + OH− → HPO42− + −O–C(O)NH2 + H2O *−O–C(O)NH2 + ATP → ADP + H2NC(O)OPO32−
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